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KMID : 0880220120500010166
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Journal of Microbiology
2012 Volume.50 No. 1 p.166 ~ p.169
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Comparison of the genetic structures surrounding qnrA1 in Korean Enterobacter cloacae and Chinese Escherichia coli Strains isolated in the early 2000s: Evidence for qnrA mobilization via Inc HI2 type plasmid
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Han Sang-Hoon
Kim June-Myung
Kim Young-Ah
Minggui Wang
Lee Yang-Soon
Chung Hae-Sun
Yong Dong-Eun
Lee Kyung-Won
Yum Jong-Hwa
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Abstract
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The flanking genetic structure of qnrA1 in Korean Enterobacter loacae was identical to that of the Chinese Escherichia coli strain, the first qnrA1-carrying strain reported in Asia. Analysis of restriction enzyme sites and Southern blot hybridization results showed that qnrA1 was transferred between E. cloacae and E. coli via Inc HI2 type plasmid.
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KEYWORD
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qnrA1, plasmid, plasmid-mediated quinolone resistance, gene mobilization
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